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Information for professionals | epilepsy foundation. Cirrhosis (end stage liver disease) is a diffuse hepatic process characterised by fibrosis and the conversion of normal liver architecture into structurally abnormal Cirrhosis. stage liver disease. cirrhosis liver.Cancer that does not respond to treatment. The cancer may be resistant at the beginning of treatment or it may become resistant during treatment.Definition of refractory cancer - NCI Dictionary of Cancer Terms Cancercenter.com glossary states that refractory is a disease or condition which does not respond to attempted forms of treatment. To read the complete definition of refractory, visit our site today.Refractory : Cancer Glossary | CTCA 31 Jan 2018 The word “refractory” in general use means stubborn or intractable, and in medicine it is specifically applied to disease that does not respond to treatment. Refractory cancer refers to cancer that may be resistant at the beginning of treatment, or becomes resistant during treatment. “We would consider What is Refractory Cancer and How Is It Treated? | Dana-Farber Looking for online definition of refractory cancer in the Medical Dictionary? refractory cancer explanation free. What is refractory cancer? Meaning of refractory cancer medical term. What does refractory cancer mean?Refractory cancer | definition of refractory cancer by Medical dictionary Information about treatment options for relapsed and refractory non-Hodgkin lymphoma (NHL). Refractory disease may be disease that is getting worse or staying the same. Relapsed non-Hodgkin lymphoma (NHL) is NHL that responded to For information about the drugs mentioned on this page, visit Drug Listings.Relapsed and Refractory | Leukemia and Lymphoma Society If your blood cancer is refractory to a particular therapy, your specialist will explore other therapies, or salvage therapies, that may treat your cancer better. For many blood cancers, there are a number of known therapies that can help to treat a person's disease. These treatments may differ in intensity, how they are delivered, Refractory Cancer: Leukaemia Foundation 23 Aug 2013 Nevertheless, there are multiple emerging classes of targeted therapies for relapsed/refractory disease, including monoclonal antibodies, antibody– drug conjugates, radioimmunotherapy, small-molecule inhibitors of cell-growth pathways, and novel chemotherapy agents. This review will discuss treatment Treatment challenges in the management of relapsed or refractory Refractory: Not yielding, or not yielding readily, to treatment. What Kind of Doctor Do I Need? Slideshow. Dental (Oral) Health Quiz. Heart Disease: Causes of a Heart Attack. Causes of a Heart Attack Slideshow. woman thinking. From WebMD Logo. Tips to Better Manage Your Migraine. Start Now Definition of Refractory - MedicineNet rapid advances in the diagnosis and treatment of the disease and the vast majority of Hodgkin lymphoma patients— over 80 percent—will be cured of their cancer with first- line treatment. And even for those patients who relapse. (the lymphoma returns following a remission) or become refractory (the lymphoma is resistant Relapsed and Refractory Hodgkin Lymphoma Relapsed, or recurrent, chronic lymphocytic leukemia (CLL) means the cancer has come back after treatment and reaching remission. Refractory disease means the leukemia did not respond to treatment. The following are treatment options for relapsed and refractory CLL. Your healthcare team will suggest treatments Treatments for relapsed or refractory chronic lymphocytic leukemia 25 Jan 2018 “Metastatic triple-negative breast cancer is an aggressive disease with a poor prognosis that tends to affect young women,” said Aditya Bardia, MD, MPH, Director of Precision Medicine at the Center for Breast Cancer, Massachusetts General Hospital, Harvard Medical School, Boston. “Currently, there is no Novel Antibody-Drug Conjugate Active in Refractory Triple-Negative 10 Jul 2012 Drug resistance or refractoriness means that the cancer is no longer responding, or is progressing to that particular agent. usually it also means that the class of agent is not likely to work either, although this is not necessarily true. For example, one can have disease progression on paclitaxel when given All Cancers : When a tumor is said to be resistant or refractory In some cases, prolongation of the platinum-free interval can improve the likelihood of response to retreatment with platinum due to partial reversal of acquired drug resistance. This phenomenon has been documented in a small number of patients with cisplatin-refractory disease who have responded to retreatment with Second-Line Treatment of Ovarian Cancer - The Oncologist